Funnily enough the one I used to take (Escitalopram) apparently has been found to begin permanently altering brain function after only a few hours of first ingestion. I was pretty happy with it. No pun intended
Also, kind of happy to be off it right now honestly, heat is something that doesn’t go along well at all with SSRIs.
However I was in a quite sorry state before... I was having several panic attacks a week. My therapy alone was also not working well, I was doing twice a week. After starting it, everything started falling into place. I never had a panic attack again.
I never had any downside whatsoever from taking them (didn't know they don't go well with summer!), including the regular complaints, it wasn't really a burden on me other than having to buy them monthly and take them every day.
Did wonders for my anxiety too.
Pointing to alterations isn’t really helpful without context. An anti-depressant should induce long-term helpful alterations in order to alleviate symptoms.