I have lived in San Diego. I have spent time in Los Angeles. I have spent time in San Francisco. I am not a stranger to large cities.
I can say with certainty I will never live in one of these places. I won't even live in Pittsburgh, which is an order of magnitude smaller than any of these places. There's no escaping people. There's no escaping politics or bureaucracy. There's no way to escape petty crime, crazy people, and noise. You can't see the sky at night, there's never any "dark".
Everything is orders of magnitude more expensive in a city. $5000/month rent? And people think this is "reasonable"? I don't even pay a third of that on a mortgage on a 2400sq/ft house. With a nice yard, decent neighbors, a good school, low crime, low taxes, the works. Our night-time intruders are turkey, deer, the occasional black bear, raccoons, skunks, and screech owls.
Do I have to drive to get anywhere? Yes.
Do I get the highest-paying jobs? Do I have immediate access to cute little bodegas and trendy little shops and night life? No.
But I can let my kids go outside and play at night. I can leave my doors unlocked. Nobody breaks into my car and steals my stereo. I can leave my house with my garage door up and all my stuff inside, and my neighbors will call/text me to remind me.
Is this an adequate trade-off? For me, absolutely yes.
I get why people like living in big cities. I will never again live in one myself, though.