The content range is very wide, and some of the most popular anime's/mangas are geared towards pre-teens.
But there's plenty of art that has no match in any other field. A list of my favorites if you want to test them out, that don't include "fan-service" (most of what you mention).
Wolf's Rain
Fullmetal Alchemist
Evangelion (includes some pandering, but the content is way too original to care)
Berserk (recommend manga over anime)
Vagabond (manga)
Death Note
Attack on Titan
Utena (old, but a very strong story about grooming and abuse)
And these are the popular ones. If you start going deeper and branching out you can find jewels, specially in manga.