For me a particularly frustrating aspect is the way the UI moves around a lot. I’m quite anxious to click anything until all the loading spinners have stopped in case I click the wrong thing. Then I could be taken to a page or feature I’ve never seen before.
Also it’s really annoying when I try to copy something from a ticket description but it starts editing the whole description field.
EDIT - I'd also like to add that as a developer, once I finish my ticket I assign it to a QA. Then I can never get back to the ticket. I'd like a really easy way to see all of the tickets I've ever completed. But completed tickets aren't assigned to me, they're assigned to QA.