Things like, the buttons on a dialog should should be a verb indicating the _action_ the user wants to take. Like "Run This" and "Go Back" instead of "Yes" and "No". (Or worse, the old Windows "OK" and "Cancel", which is rife with ambiguity in so many cases.)
And the tone of the document was that it was intended to be useful to _all_ user interface designers of all software and on all platforms, not just OS X. I just skimmed over the current edition and as far as I can tell, these days it's basically just about how to stay "on brand" with the Apple experience when writing your own UI.