Why? You are doing the inference in the same request, which is synchronous from the perspective of the caller. The request can be memory-intensive or cpu-intensive. And the issue is you can't efficiently consider all the workloads for a single machine without being bottlenecked by Python.
I would say that the problem is in your approach trying to use the webapp hammer for all the different flavors of nails in your system, using a language that isn't suited for concurrency. What I would do is decoupling the validation/interface logic from your models via a queue. This way you can scale your capacity according to workload and make sure the workload runs on hardware most relevant to the job.
I have a feeling trying to throw a webapp at the problem might not solve your root issue, only delay it in time.