- The lack of mixed use zoning makes it just that much more likely that one live so far from their workplace. The choice is too often "a house far away from everything" or "a high-rise close to the noise, smells, and un-pretty sights of town"
- There's so little space to build offices cities end up having super-dense downtowns, with very tall, expensive and crowded buildings. This is great for office real-estate, but terrible for everyone else because it means traffic. Since cities tend to have only one mega-downtown, cause zoning in the USA is pretty adamant in grouping everything together, things get even worse, because everyone is moving in the same direction at the same time.
- This hyper-dense core, but hyper-sparse suburb outskirts in cities make it very hard to bike to work; many people in the USA wouldn't even consider it an option. It's also hard to build efficient public transit. The routes that make sense are radial, so they might be good to get to work, but inefficient for leisure. Things are so far apart in the suburbs one it's hard to put stations close to everyone where they live.
The fact so many people prefer to not leave their home for work should be considered a moderate victory for remote communication technology, but an abysmal failure in urban design.