Absolutely. This is where the real dependency bloat in ecosystems like npm come up. You may only include a handful of reasonable dependencies, but each of those have dozens of their own dependencies, and so on and so on.
However, I think the blog post reflects a strong desire of many developers (I am one of them.) Achieving this vision, at least in commercial software, can be a utopian dream.
I also get away in my professional life using it for pretty much nothing and it's great. There's a reason Ryan Dahl moved on to Deno.
People who think it's somehow necessary or integral to getting a website going are deluded hypebeasts.