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I always keep my monitor's brightness low, and never experience eye strain. My technique is to hold a sheet of white paper up next to the screen, and turn down the display's brightness until a window with a white background appears to be no brighter than the paper.

I keep brightness low as well (and have since forever), but still have eye strain (and have possibly developed some eye issues) and dry eyes.

Supposedly, it's important to keep blinking regularly as well, which I think I do too.

I guess the only option might be to switch to no-backlight screens (eInk or LCDs with reflective screens), but they are pretty expensive for an experiment in any decent size.

I always keep mine about 70-80% brightness cause I think it look clearer. Anyone else feel better with low brightness?

It probably helps if you are just before getting glasses

Same. I keep my room well lit — be it natural or artificial, and keep screen brightness below 40% most of the time, and it really helps.

Windows 10 has a auto dim feature that turns down brightness as sunsets