So, if you have a 95% chance of going 10x that's great, but the question is: can you handle a 5% chance of having being potentially ruined for at least a decade? If not, then you cannot take the bet despite the fact that EV is super high.
Put more extremely, if I offer you a 99% chance to take make one billion dollars (legally) and a 1% chance of being killed, would you take it? I definitely wouldn't.
How about the following? I offer you an unfair coin flip advantage of 51% versus 49%, we're going to flip 1 million times, each time the bet is 1 dollar. Would you take it? I would.
The heuristic that poker teaches is: take a lot of small bets with huge upside with little to no downside. It doesn't matter how slim the chance of winning is. Slightly more nuanced (still a heuristic): the chance should be about as big as your volume of chance-taking. Say, you take 10000 chances, then the slimmest chance you can take (on average) is 1/10000.