You picked mainly data science python projects. It would make more sense to compare with other python web frameworks.
django, 1101 open, 32662 closed
cherrypy, 218 open, 1505 closed
starlette, 31 open, 570 closed
pyramid, 70 open, 966 closed
falcon, 168 open, 789 closed
flask, 14 open, 2318 closed
fastapi, 1044 open, 1855 closed
Fast api has one of the worst ratio regarding open/closed issues.