I'm hesitant to do this because occasionally I've been blocked by some second factor for password resets, but at that point I've confirmed the email.
Though I tend to just block the sender domain (because they're always from services that I'm never going to use anyway) and ignore the email just on the off-chance that someone is trying to scam me in some weird way. (Plus I really just don't care enough to deal with it unless the email is clearly important or sent by an actual person)