The NHTSA doesn't care about pedestrians because Europe does and by proxy that covers basically everything in the US except trucks. Speeding stats are basically useless given the state of speed limit compliance in the US. Current breathalyzers suck for a variety of reasons though if the OEMs start adding them they might suck less due to incentive alignment. Seat belt interlocks are fine and probably the only politically tractable thing on the list.
Wanna make roads safer? Reduce the number of interactions between traffic of differing speeds, reduce the speed differences at which interactions happen and where possible modify these interactions to reduce accident frequency (e.g. roundabouts vs n-way stops). And before a certain group of jerks gets annoying, my definition of traffic is "all road users".