It worked pretty well for the most part, and I would recommend looking into this for most teams since it's a pretty quick win. Most typecheck steps went from minutes to low-double-digit seconds (admittedly still slower than I would have hoped).
But occasionally there would be gigantic spikes back to minutes for seemingly small changes that seem like they should have been incrementally check-able. I suspect these might have something to do with circular dependency chains, but didn't have bandwidth to dig deeper.
I wish TypeScript's incremental checking mechanism and file formats was a bit better documented and less opaque, so people could better reason about and optimize typechecking performance, and possibly build support into other systems to perform & share some of the analysis they're already doing to avoid wasted work. That and to make it less of a giant blob for the entire codebase, and more of a set of files that are incrementally and individually update-able for better cache granularity and faster updates.