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Comment by insaider | Hacker News Reader

I've been struggling with the same sort of thing for 8 years now. I've been to dozens of doctors in several different countries but never got a proper diagnosis.

From my own research and observations I'm quite confident it is, as you elude to, an auto-immune related disease. The two major triggers for me are exercise; particularly anaerobic e.g weightlifting, and alcohol. Alcohol actually alleviates the symptoms for a day or more and then undoubtedly i'll struggle for a few days after that. Which points to alcohol's suppressive effects on the immune system.

I really really hope this, and similar research[1], turns into something tangible

[1] https://med.stanford.edu/news/all-news/2019/04/biomarker-for...

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I'm in the same boat. My main problem is atypical facial pain and I don't have a solution after visiting several neurologists and other specialists

I've been dealing with autoimmune issues for years as well. I have yet to find a doctor that is willing to help me get to the bottom of it. I too have seen doctors in multiple countries.

For me, the trigger is carbohydrates. Doesn't make having a good social life easy. I'm on a forced ketogenic diet because of it.

Yes, for me as well. I would say, if you are doing Keto, watch your Omega 3/6 balance. My brother did it for a year and focused on mainly red meats. He lost a bunch of weight but the inflammation from the Omega 6 is what probably caused his ankylosing spondylitis and triple bypass.

I quickly became manic when I only eat red meat.

> the inflammation from the Omega 6 is what probably caused his ankylosing spondylitis and triple bypass.

How confident are you that this is the case? This is now the second story I've read of someone on a keto/carnivore diet having to get a triple bypass after eating too much red meat. Was his omega-3/omega-6 ratio really that much worse than that of the average person not on such a diet (not that that's a great standard to compare against, but the average person is also not getting triple bypass surgery)?

I know there's a lot of evidence against the notion that saturated fats cause CVD, and omega-6s and inflammation is a compelling case, but I'm worried we're missing something.

You know that's actually really good advice. That is something I should be more mindful of. Thank you

Interesting, why do you think carbs are a trigger for you? I always have bad IBS symptoms when the other symptoms flare up but I haven't been able to find any foods that seem to directly correlate with it.

I don't think, I know. After a lot of trail and error it's a night and day difference.

Intermittent fast and eat very low carb – no stomach problems. Eat too many carbs more than ~25-35 – stomach problems.

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