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Comment by GenerocUsername | Hacker News Reader

Article says cause might be viral proteins in the epithelial layer of intestines, and then assumes those proteins are present due to infection, leaving out the possibility viral proteins are finding their way into youch children's intestines through other means... Such as vaccinated breastfeeding women.

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> leaving out the possibility viral proteins are finding their way into youch children's intestines through other means... Such as vaccinated breastfeeding women.

I struggle to find where it suggests that vaccinated breastfeeding women have somehow contaminated toddlers?

On contrary, it seems to me that it implies a secondary infection with an adenovirus to be the cause:

(citation)

"Following infection with SARS-CoV-2 virus, viral reservoirs have been reported and could over time lead to repeated super-antigen mediated immune cell activation as shown in Multisystem infammatory syndrome, MIS-C.

If such viral reservoirs are present and a child is subsequently infected with AdV, this superantigen-mediated effect could be much more pronounced and potentially give rise to immunopatthology."

And at the moment it's just an hypothesis.

An easy way to exclude this hypothesis would be to check the ages. You’d see some kind of hard drop past ~1.5 years. Skimming source 2, it seems like they’re talking about a much wider range of ages, but still it’s be worth breaking down the data in detail.

Not a doctor, have three questions:

Is what you describe a common issue with other vaccines?

Is this way of "infection" really harmful?

If yes, would the effect of a real COVID infection via breastfeeding be less or more dangerous

The MRNA jabs by definition induce the recipients body to produce viral proteins, so no, other vaccines would NOT cause similar issues. It's not infection per-se, but could explain unprecedented and novel downstream effects. Breastfeeding during an active COVID infection could cause similar results, though infants and young children lack the ACE-2 receptors the virus most actively infects

Article specifically says that "SARS-CoV-2 infection can result in viral reservoir formation" and that this may lead to repeated release of virus to body. This may cause the rise of immune activation and "SARS-CoV-2 spike protein that bears resemblance to Staphylococcal enterotoxin B, triggering broad and non-specific T-cell activation. This superantigen-mediated immune-cell activation has been proposed as a causal mechanism of multisystem inflammatory syndrome in children".

As MRNA vaccine do not make recipient body to create replicable viral protein, I fail to see the mechanism that would create this viral reservoir and article does not even mention this as possibility. Moreover, MRNA vaccine itself is not injected into your blood, but to muscle tissue, so how would that MRNA vaccine get into milk? Especially if you compare it with much much higher probability of child simply being infected with live virus.

Please can you explain how a weakened virus, infecting but not overwhelming an immune system, or an adenovirus modified to produce such proteins, or direct injection of these proteins differ from mRNA vaccines in their ability to leave proteins in a person?

I don't understand if you're distinguishing non-COVID vaccines or non-mRNA vaccines when you say other vaccines won't have the issue.

The amount of spike protein that manages to circulate the blood stream is super low, like orders of magnitude lower than in a typical live infection.

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