While the US federal government spends over $20 trillion a year. This isn't comparable at any level - regardless of any snake-anatomy analogy.
I'm not sure what your definition of a "member state department" is? But knowing something of the political set-up in a number of EU countries, none are under the "sole control" of the EU (commission I guess you mean?).
[1] https://ec.europa.eu/info/strategy/eu-budget/eu-budget-added...