Example: people overdose on Tylenol, and we may have to give them NAC (N-acetyl-cysteine) to boost their depleted glutathione levels and get rid of the toxins.
Another example: people ingest a poison, and sometimes it's appropriate to make them drink activated charcoal so it can bind the toxins. These types of "Detoxes" are also common (but over-used) in the alternative world.
Another example: with some infections, you can't give too many antibiotics at once or it will overload the body's detox capacity, so things are done to help.
Another example: 9/11 workers who were exposed to massive amounts of toxins from burning building materials afterwards suffered from that exposure. Conventional medical doctors came up with detox protocols including the use of Far Infrared Saunas to help decrease the toxin load in their bodies.