In my experience, women are interested in hearing about the guy's passions, not less so if that passion is building a transformative startup.
Telling her that she looks gorgeous? Really?
She: Do you think she's gorgeous ?
He: She's the most beautiful girl I've seen.....in the past 30 seconds
I don't think it's fair to make that assumption. Passions are awesome, but they'll lose interest if you start describing the intricate details. That's not only true about women, but most people in general. The trick is in how you describe, and not what you're describing.
One remarkable girl had me asking questions for half an hour about shoes, for example. I hate shoes.
The idea behind speaking about your passions is to tell it via a story and also create an emotional connection with the women as you're doing it.
(fortunately my girlfriend has gone from a being a biotech tech worker at a big pharma company to constantly asking about how to start a startup...)