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AIUI mosquito-borne illness is estimated to have killed more than 4% of all of the humans that have ever lived https://www.realclearscience.com/blog/2019/10/03/has_malaria...

"Malaria may have killed half of all the people that ever lived"

https://www.nature.com/articles/news021001-6#:~:text=Malaria....

I think people forget quite how long the population tail in Africa is and people also forget that malaria used to be endemic to Europe.

And that previous attempts to curb the reign of mosquitoes include things like "draining all swamps everywhere".

Take a look at the coastline of Long Island on satellite maps, and all the scars left by that time they tried to eliminate all of the salt marshes to get rid of mosquitoes near NYC.