It'll all come down to who they get to run it, how well they run it, and if they can consistently get the attention of founders. A16Z certainly has the brand and money to make a real go of it.
I wonder if they know what makes YC special and if they can offer the first head-to-head alternative.
Edit: After another quick look, seems like they may just be targeting executives at existing successful companies, in which case they're not likely to create a legit alternative to YC at all. Oh well.