I have. It's painfully slow.
But slowness isn't really the problem, the problem is that it's unpredictable.
I wait for the interface to be fully loaded, so I click on a text box and i start typing. Then FU--ING something takes the focus to some other element in the web page and now i'm typing random shortcuts (like reassigning tickets, changing status or whatever).
It's painfully slow but the real problem is that it's unpredictable in its behaviour.