Cost, the article says approx 50-85c more per gallon.
I understand that you can also end up with exhaust valve deposits, but that's not something I've seen personally. Aviation engines (especially those used for training, which is a large proportion of the piston fleet) have incredibly short inspection intervals in any case.
Looking at my own local airports ( e.g. http://www.100ll.com/showfbo.php?HashID=d0f7e0afbdcf9b9a7cde... ) the price goes higher to often over $7.00/gal, though that's for "full service" (I don't know what that means, though).
Self-service means there's a pump with a credit card and a really long hose, that would look familiar to what you see at an auto filling station.