The conclusion said it is less effective.
The messenger RNA (mRNA) boosters were highly effective against symptomatic delta infection, but they were less effective against symptomatic omicron infection. However, with both variants, mRNA boosters led to strong protection against Covid-19–related hospitalization and death. (Funded by Weill Cornell Medicine–Qatar and others.)
Don't get me wrong, I believe in the vaccine, but I think we are still far away from one vaccine that kill all the the mutations.