As a user, if you build every python package from source, it's ok. But if you a maintainer of an OSS project and you need to publish binary packages for it, then you will hit the trouble. Binaries built on Ubuntu 20.04 can only support Ubuntu 20.04 and newer. So you'd better to choose an older Linux release to target broader users. Now most python packages choose CentOS 6 or 7. See https://github.com/pypa/manylinux/issues/1012 for more details. They need help!