South Russians don't feel pretty much any affinity for Moscow. This can potentially launch a chain reaction of Russia's disintegration.
Russia's Far East will almost certainly secede for its ethnic makeup, and the only ethnic Russian stronghold in the region being uniquely anti-russian (as a state) for so many reason, the latest being harsh draft, and using Far Eastern youth as a cannon fodder for the last 8 years.
Urals, and Siberia are uniquely resource rich, and they will want the money for themselves. There was a precedent: "The Republic of Urals" was a semi-functional regional autonomy for a few months in 1991.
Kalmikia, and Tatarstan can secede as well.
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Militarily wise, Russia is at its weakest since its loss in first Chechnya war.
They just wasted at least 50% of Russia's current standing force on Ukraine, most of which is now stranded in Belarusian woods without supplies, and fuel, or destroyed in Ukraine.
Their bases near Ukraine are now standing empty.
My many contacts in Vladivostok report the same thing: military brass there "is thinking"