The Dune wiki, for what it’s worth, describes them as a Native people:
Part of the appeal of games is harmlessly doing things that shouldn't/can't be done in real life. I think the millions of 'people' I've 'killed' across various bloodsport-themed FPSes over the last couple decades is a greater evil if we're talking about shoehorning IRL morals into consequence-free virtual spaces. And if you disagree, why? Is mass murder not worse?
Maybe I'm just oversensitive to moralizing in video games, but this line of argument was no less tired over a decade ago.
There is no support for video games glorifying rape. There shouldn’t be support for video games glorifying colonialism or racism.
And how far do you stretch this notion, can we still play games about ancient Rome for example?