The one that has really gotten my goat is when you tag a photo with your friend on it. Even if you have privacy set so that only your friends can view your photos, if you tag your friend in one of your photos, ALL OF THEIR FRIENDS CAN NOW SEE IT.
You can't change this setting. It's called something like "Friend of friends can see tagged photos." You have no control over this, and the only one who can change this is your friend that you tagged.
This is now forcing me to never tag any of my friends, because I don't want strangers seeing my photos. It means effectively that I've lost control of my privacy on my photos, and that's something that is enough to drive me away from Facebook permanently.