My problem with games like Factorio (and more recently Oxygen no Included), is that after I get addicted and get up past 100 hours of gameplay I start to question what the hell I'm doing with my life. Up until that point it's great fun designing, building, and optimizing, but then a switch in my head flips. I start to become anxious about the fact that I was excited about getting better at skills in a virtual world. Usually around this time I start watching videos of more advanced builds, and then become increasingly depressed about the idea of sinking 1000+ hours into a game, when I could just be building something in the real world, or out riding my bike. This is usually the time I put the game down and never play it again.
I think the problem for me is that these games give me the illusion of learning, building, and accomplishing things, which my little engineer brain loves. But once I come out of the haze of addiction, I realize it's nothing more than an illusion, and I just stomach going on.