However, in temperature below zero at -5 degrees Celsius for example, half life of DNA is actually 10,000 years or more. https://en.m.wikipedia.org/wiki/Ancient_DNA
Still, this would also only allow 200 years of freezing before more than 1% of bonds would have been broken.
The third and probably most viable option is to wake up the crew every 200 years to repair accumulated DNA damage.
Also, a small percentage of the crew would probably be awake at all times for repairs etc., so the crew could rotate every 200 years.