Is there a miniature ASIO soundcard planned for one of the slots? Not needing to carry an external audio interface around when working within a DAW is a major factor that's keeping me on MacOS (both pro audio and consumer use the same driver there).
I don't know how much licensing would cost, but Framework could possibly offer a driver for the internal card as an addon. Then the slot could be used for a small headphone amp which would be more third party friendly I think.
https://en.wikipedia.org/wiki/PC_Card
You could get standardised addons for laptops, but I guess they disappeared due to lack of interest/better alternatives.
It's weird how the world goes around in circles.
It'd be particularly cool to get balanced outputs.