There have been a couple of experimental processors on which professors have published papers claiming an order of magnitude lower power consumption than Ambiq claims for their chips. Assuming that's true, I don't know how much of that is a question of process variability (e.g., maybe 5% of Ambiq's chips also get such low power consumption) and how much is a question of other engineering compromises (e.g., maybe ARM is a particularly power-hungry architecture, as the lower power consumption of the GD32VF chips suggests, or maybe the experimental chips only worked between 47° and 47.5° and even then they crashed once an hour).
By "really low" do you mean active power more like 1 microwatt, 10 microwatts, 100 microwatts, or a milliwatt?