Given that Omicron is assumed to have replicated in an animal population (mice) for a year, we should expect there to be other variants in animals. Even if we managed to vaccinate all humans at the same time, we'd likely see a new breakout a year or so down the line when immunity wanes in the human population.

Covd19 has been endemic for two years now. And it will be endemic until we find better vaccines. At that point, we'll probably be ready to wipe out the flu as well.