Robustness against future strands and acceptability to covidiots are the two big problems where I live, at least as far as I can see.
The article already mentions an Indian manufacturer getting up to speed with this vaccine, with 150 million doses already manufactured.
If you search for “lack of covid vaccines in Africa” there are many, many results.
I’m tempted to say you’ve asked the question with a very Western mindset, not really considering less developed nations.
India had vaccine manufacturing already, with over a billion doses of locally produced covid vaccines dispensed and much more than that produced. Clearly the patents and pricing weren't debilitating problems.
May 17th, 2021
https://www.theverge.com/2021/5/17/22440292/vaccine-waivers-...
There were shortages, but AFAICT those weren't related either to pricing or to patents. The government ordered what it thought necessary, the manufacturer set up production to match that and delivered doses as ordered. Then more was needed and scaling up further took time.
Overall, I can't see reason to count the three problems in the headline as big problems for India.
Like the people who worry about the spike protein in the vaccines, but still don't realise that the virus contains exactly that protein and many more reasons to worry.
peekaboo knows that noone's taken booster shot 5, let alone 25, so noone with five doses could possibly have gotten very sick and said anything at all. He's just making five doses sound ridiculous. He has no rational argument.
He could have a rational opinion — a vaccine against an older disease is often given in five doses or even more, and he could have a general, well-reasoned opinion about vaccine doses. (Google for "during childhood, five doses are recommended, with a sixth given during adolescence" if you want to read about that.)
AFAICT peekaboo hasn't ever suggested that the vaccine for that disease is idiotic, and he also hasn't suggested reasons why why covid should require fewer doses than that disease. He just makes stuff up, and that's a fine example of what I meant by "covidiot". (peekaboo: If you have posted any of that, perhaps elsewhere on the web, please do post links and I'll apologise.)