Of course, if the game does need heavy-duty serialization of everything, all bugs are potentially deadly. And this is largely the case for the line-of-business, social, and productivity apps, because that data is considered mission-critical. Corruption is not OK, reverting to backups is to be avoided. When a game has that kind of requirement, things get a lot tougher - and so games have naturally evolved to favor minimizing the save data to nothing or a few stats.
And this is borne out by looking for contrapositives. There are two genres that have a history of tending to be buggy because of some form of long-term data corruption: Large-scope RPGs and turn-based strategy games. It's hard to reach the bugs in those games, so it's also hard to fix them.