Portions of a program or library might be written in assembly for performance. This list should give an idea of the type of software that does this

  $ cd /opt/homebrew/Library/Taps/homebrew/homebrew-core/Formula
  $ grep depends_on.*nasm * | sed 's,:.*,,' | xargs grep desc
  dav1d.rb:  desc "AV1 decoder targeted to be small and fast"
  dssim.rb:  desc "RGBA Structural Similarity Rust implementation"
  ffmpeg.rb:  desc "Play, record, convert, and stream audio and video"
  handbrake.rb:  desc "Open-source video transcoder available for Linux, Mac, and Windows"
  isa-l.rb:  desc "Intelligent Storage Acceleration Library"
  jpeg-turbo.rb:  desc "JPEG image codec that aids compression and decompression"
  libass.rb:  desc "Subtitle renderer for the ASS/SSA subtitle format"
  libavif.rb:  desc "Library for encoding and decoding .avif files"
  libvmaf.rb:  desc "Perceptual video quality assessment based on multi-method fusion"
  lrzip.rb:  desc "Compression program with a very high compression ratio"
  mozjpeg.rb:  desc "Improved JPEG encoder"
  mvtools.rb:  desc "Filters for motion estimation and compensation"
  openh264.rb:  desc "H.264 codec from Cisco"
  openj9.rb:  desc "High performance, scalable, Java virtual machine"
  pce.rb:  desc "PC emulator"
  ppsspp.rb:  desc "PlayStation Portable emulator"
  rav1e.rb:  desc "Fastest and safest AV1 video encoder"
  vapoursynth.rb:  desc "Video processing framework with simplicity in mind"
  x264.rb:  desc "H.264/AVC encoder"
  x265.rb:  desc "H.265/HEVC encoder