An absolute must have is BetterBibTex (https://retorque.re/zotero-better-bibtex/), which adds better Citekey management and, my personal highlight, "export on add" functionality. In short, everything I save into a specific folder in my library gets exported as a .bib file right away. That way I can click a button in my browser and have the citation ready in my LaTeX editor, Word, or Obsidian (https://github.com/hans/obsidian-citation-plugin) within seconds.
The latest beta also adds full Markdown export for Notes. I tend to keep my notes on papers in Zotero, attached to the paper, but export them for filing in Obsidian (which I then feed into MkDocs for our work group's large repo).
Unless you need Apple Pages support, which Apple keeps to itself and only sells for mighty moolah to a select few, Zotero can do anything EndNote can do, is Open Source, and with that won't drive your PI up the wall with yet another expense.