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Proton is a fork of Wine. Just more tailored towards steam games.

actually, proton is two things: wine+dxvk. dxvk is a windows (!) program that translates directx to vulkan. between the two of them theyre all thats needed to run games.

proton is in addition funded and tested thoroughly by a critical audience, linux gamers ;)

I've had no luck with Photoshop in Wine or VB seamless mode (PS's custom window decorators are probably the reason for the latter). A full-desktop Windows VM is still good enough with guest extensions though, so I can easily resize the whole Windows desktop with just a maximised PS window inside.

VirtualBox is a horrible way to run games of any kind. The driver support for graphics is miserable.

WINE is an acronym for "Wine Is Not an Emulator"

Some software are hit and miss, or just fail to work on wine. Big one for a lot of people is the Affinity suite.

From what I saw only old versions of the software I need run and when they run lots of little things are missing.

I would call software with that amount of quirks and performance issues pre-alpha quality.

So, I can use my MacBook for Adobe for now until they come to their senses.