Simplistically you would need:
A source of energy, aka a star, at the very least there are 10^22 of them
A rocky planet situated in the habitability zone of the star (and this is lacking the imagination for life in other kind of environments).These guys are common.
The creation of chemical self-replication with a stable set of compounds (The hardest part for me, but far from impossible)
The appearance of intelligence as an evolutionary trait (nature loves that explore/exploit game)
Time
We modern humans lived 99.7% of our 200k year history entirely unaware there were other people and land a mere "earth radius" away, we may as well repeat that story in a cosmic scale.