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Not according to this PR on Jan 17, 2011: http://www.apple.com/pr/library/2011/01/17Apple-Media-Adviso...

"At my request, the board of directors has granted me a medical leave of absence so I can focus on my health. I will continue as CEO and be involved in major strategic decisions for the company."

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Right, he was on medical leave. He retained the title and was involved in all major strategic decisions. Tim Cook was left to handle daily operations and was essentially acting CEO. While I would be surprised if Jobs didn't know about a lost iPhone given his heavy involvement in the company I also don't see how this isn't a daily operations issue falling to Tim Cook.

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