Region outages happen, which is why the guidance is to build in multiple regions, but even Amazon sometimes doesn't take their own advice. Sometimes the reason is good, sometimes it isn't.
The cli is gorgeous, the web gui is terrible.
At a previous job where we needed to always be up, our disaster recovery plan assumed that the us-east-1 site had been hit by a meteor (not literally, but that's how we explained it to each other to put ourselves in the mindset.)
https://aws.amazon.com/about-aws/global-infrastructure/regio...