As a hacker rather than a gamer, the concept of a programmable set of LCD keys next to the standard keyboard is extremely interesting for native app development. I hope that particular feature is copied into a subsequent Macbook Pro release.
It's really bringing the innovations pioneered by the iPhone (programmable UI rather than built-in keyboard) back to the laptop.
Among other things, you could have custom glowing save/search/email keys within Word to increase the accessibility for the average joe. They might not be able to find control-F, but they can see the key in their top 10 list.
For Mail.app, Keynote, etc. you'd have different sets of keys (show presentation, download attachments, etc.)
It could get even more interesting if different keys are available in different modes within the same app, like tooltips to the nth degree. For example, each new emacs mode could light up 10 hotkeys for useful functions associated with the mode (compile, jump to, view in browser, and so on).
tl;dr: programmable LCD keys are a very interesting way to combine the best of iPhone-style programmable UI and keyboard-style haptic feedback.