Covid epidemic curves globally similarly showed no change as a result of mask mandates.
And a massive outbreak of influenza was not deterred by a fully masked U. Mich campus.
They seem to provide a psychological benefit to some though.
It's an area where precision can account for large changes in meaning. For example, it's true that the holes in an N95 mask are much larger than the viruses, but they're not much larger than the airborne droplets that contain the virus. There are ways to truly aerosolize the virus itself, but that's not how this virus is transmitted. He couldn't be sure of the transmission, but he would be wrong to assert that masks couldn't help.
It's possible that he was just dumb, or that he said something slightly different from what you report. Even an expert can be Just Plain Wrong.
Science as a whole always works from incomplete information, and revises itself. That happens even in the hardest sciences, like the way Newton's theory gave way to Einstein's. What's the same is the underlying process of trying to continually improve.