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So what are you proposing? Trying to avoid everything that might cause an immune system reaction? That will eventually lead to the immune system really running amok...

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I'm just saying that a wheat and yeast-free diet has reversed Hidradenitis and many systemic inflammation symptoms for me. In trying to understand _why_ it became clear to me that yeast (and maybe wheat) trigger an inflammatory response in our innate immune system - by design. So it's probably not a good idea to eat yeast unless you want to up-modulate your immune system (inducing inflammation). Even if your body can down-modulate, isn't that just causing a sensitivity imbalance similar to diabetes and glucose?

For example, Dectin-1 is one of many innate cellular receptors that launch inflammatory responses when Bread yeast (and others) is detected (and possibly 1,3 beta glucans from wheat). We are in a genetic war with saccharomyces cerevisia, inside of our DNA. And not just us, all animals need to be in this war, because otherwise we'd die.

https://en.wikipedia.org/wiki/CLEC7A

So if all this is true, does it make sense to put yeast extract in your gravy tonight?

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