Personally I love scientific pitch [1] (C=128Hz, A=~432Hz, 12-TET), I wonder why the world is still using A=440, it doesn't make sense to me. Powers of two is the way to go.
I don't see any advantage of using an arbitrary frequency such as 440 oscillations per second for A instead.
Your argument seems to hinge on being able to know the frequency of a specific “C”, but how often is that necessary?