I did this one time. Ran over a pothole and bottomed out. As I'm replacing my front tire I look to my rear tire and see that it's also flat. That wasn't even the cherry on top. At that point I had my front wheel off and tried putting on the spare anyways.
I had a Kia Stinger GT and the GT version has Brembo brakes which have a much larger caliper than the regular version. Well QA at Kia never thought to check if their spare tire actually fits with the larger caliper. Spoiler alert: it doesn't.