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FreeCad is a generic parametric CAD software. It is not designed for houses, but it allows to create constraints-based designs and is scriptable through python.

So not a 100% match but it checks several of your items. If you are considering something as remote as openSCAD, I think you should give a try to FreeCAD and look at a few tutorials (its workflow is not the most intuitive thing)

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See Arch[0] module for FreeCAD.

[0]: https://wiki.freecadweb.org/Arch_Workbench

> it allows to create constraints-based designs

I've never seen an architect using a constraints-type CAD design workflow.

I always thought constraint-based design is typical mechanical engineering thinking.

Do architects work with constraints as well?

> I've never seen an architect using a constraints-type CAD design workflow.

Take a look on PARAM-O[0], the visual scripting solution for Archicad powered by VisualScriptEngine.[1]

Also, here is VisualScriptCAD[2], based on VisualScriptEngine.

[0] https://graphisoft.com/param-o

[1] https://github.com/kovacsv/VisualScriptEngine

[2] https://github.com/kovacsv/VisualScriptCAD

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