I didn't say they're stupid, I said their fools for believing what is obvious a bunch of politically motivated lies, science is no place for emotion.
No, you said "while believing anything Trump says without question."
If we can't change people's mind with the truth, what possibly could make them realize they have been duped?
Packaging matters. People are emotional and make rarely make factual determinations in a vacuum. Your attitude in our conversation so far tells me that you have a near-zero opinion of their intellect and have no idea why they believe what they believe (ie you say that they believe 100% of what Trump says, but 10 seconds later acknowledge they'll boo him at his own rally). You most likely come across as smug and superior in these conversations so while you may just be explaining that mRNA therapies have been in development for decades they will see it as an attack on them... Logical? No, but it's how humans operate. Maybe you're perfectly logical but I kinda doubt it.
Lets use creationism as an example because it's what I have the most experience with. You can argue until you're blue in the face with facts and won't get anywhere most of the time -- there were certainly people who had that experience with me 15-20 years ago. Looking back I wasn't interested in the facts. The Adam and Eve story had to be literal to explain original sin, which had to be a thing to explain Jesus' sacrifice which was one of the most central things I believed in. So when you'd crush me with facts demonstrating that the earth cannot be 6,000 years old you'd actually be tugging at the single most central thing I believed. Good luck.
I was reasoned out of young earth creationism, but I had to be in a place where Jesus was also on the table to be discussed. It took about a year from "oh shit, that's how radiometric dating works" to "uh yeah, none of this makes sense." Open discourse was the only way that was possible -- the talk.origins archive, books like Why Evolution is True by Coyne, lectures by friendly scientists, ect.