This is the key distinction. If you charge money, from the beginning, most of your content moderation woes go away.
At Transistor.fm we host podcasts and charge money for it (starting at $19/month). We've had very little problems with questionable content.
We're a counterpoint to the narrative here: small (4 full-time people), profitable, and calm.
> Even if you just hosted audio
Most DMCA takedown requests these days are handled through the big podcast directories (Spotify, Apple Podcasts). We haven't had to write/implement any fingerprinting tech.