Really depends on what you mean by large. If you mean truly large, you will need a cluster to train it in any reasonable amount of time. You’d probably want to look at servers built on the HGX platform (8 A100s per server). We use servers leased in bulk from traditional server providers (think Dell, HP, etc). If you mean more like “as large as personally affordable”, then you’d probably want to look at something like the RTX 3090, if you can get lucky and find it at MSRP, it has 24 gigs of memory. Nvidia also has their workstation cards with up to 48 gigs if I remember correctly, but if I were buying cards for myself, I would wait until I could get two 3090s somewhere close to MSRP, instead of paying the markup on the workstation cards (unless you want to have more than 2 in a workstation, in which case you’d need to go for those)

Totally depends on your budget. The DGX A100 [1] is quite good if you have a fat wallet

[1] https://www.nvidia.com/en-us/data-center/dgx-a100/

2 x 3090FE is the best bang for your buck.